OCT Eccentric Fixation and Amblyopia in Children

Launched by STATE UNIVERSITY OF NEW YORK COLLEGE OF OPTOMETRY · Jan 26, 2023

Keywords

ClinConnect Summary

This clinical trial, called "OCT Eccentric Fixation and Amblyopia in Children," is studying how certain eye movements and sensitivities relate to amblyopia, a condition where one eye does not see as well as the other. The researchers want to understand how these factors might affect children's vision and overall eye health. The trial is currently looking for participants, specifically children aged 4 to 16 who have amblyopia with specific visual challenges. To qualify, children should have a certain level of vision in their weaker eye and meet criteria related to eye alignment issues, such as strabismus (crossed eyes).

Participants in the trial can expect to undergo tests that help measure their eye movements and sensitivities. There are two groups in this study: one group will receive patching treatment, and the other will focus on foveation therapies, which involve exercises to improve vision in the weaker eye. It's important to note that children born very prematurely or those with certain medical conditions affecting their eyes may not be eligible to join. This study aims to gather valuable information that could lead to better treatment options for amblyopia in children.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. children with best-corrected visual acuity (BCVA) of 20/40 (equivalent to 0.3 logMAR) or worse in the amblyopic eye (ranging from 20/40 to 20/400), and interocular difference of BCVA was at least two logMAR lines,
• • 2. ocular causes of amblyopia that were identified as refractive(i.e., anisometropic, strabismus, or strabismic-anisometropic.
• • Anisometropia included interocular difference of spherical equivalent \>=1D or interocular difference of astigmatism cylinder magnitude \>=1D;
• • strabismus included those with deviation \>=10PD or good alignment after prior strabismus surgery;
• • combined type included those who meet the criteria of both anisometropia and strabismus.
• • For the patching group, we will enroll 15 children with strabismic amblyopia who are prescribed patching treatment. Age: 4-12 years old.
• • For the foveation therapy group, we will enroll 15 children with strabismic amblyopia who are prescribed foveation therapies. Age: 8-16 years old.
• Exclusion Criteria:
• • born before 32 weeks gestational age;
• • neurologic, developmental, or systemic illnesses known to be associated with ocular pathologies;
• • congenital or acquired macular pathology.