HEPA, PM2.5, and Cardiometabolic Health

Launched by UNIVERSITY OF SOUTHERN CALIFORNIA · Feb 7, 2023

Keywords

ClinConnect Summary

This clinical trial, called HEPA, PM2.5, and Cardiometabolic Health, is looking at whether using special air filters (HEPA filters) in homes can help improve health, especially heart and metabolic conditions, by reducing harmful tiny particles (PM2.5) in the air we breathe indoors. The study is currently recruiting participants who are between 65 and 84 years old, do not smoke, and have had a higher body weight in the past. Participants should also live in Los Angeles County and be comfortable speaking either English or Spanish.

If you join the trial, you'll be part of a study where some homes will use these air filters for a longer period. The researchers want to see if this makes a difference in your health. However, you won't be eligible if you have certain health issues like diabetes, active cancer treatment, or if your home has already had HEPA filters installed. This study is important because it could help us understand how to better protect our health from air pollution, especially for older adults.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 65 and 84 years old;
• • Nonsmoker for at least 1 year;
• • History of BMI ≥ 25 kg/m2 in the past based on EMR information;
• • Either an English or Spanish speaker;
• • Live in the Los Angeles County.
• Exclusion Criteria:
• • History of diabetes (both type 1 and type 2) or degenerative disease of the nervous system (Alzheimer's disease or dementia);
• • Currently have active cancer treatment;
• • The residential house has already had HEPA filters;
• • Participants will move out of the current house in the next 2 years;
• • Participants will spend more than one month living outside the primary home;
• • Have any health conditions that prohibit collecting health and covariate data and biospecimen;
• • The residential houses are not feasible for setting up air purifiers and air pollutants monitors;
• • Have high blood glucose from finger stick test (\> 200 mg/dL).