Traditional Dietary Advice Versus Reassurance-alone in Postprandial Functional Dyspepsia

Launched by SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST · Jan 30, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at different ways to help people with a common condition called functional dyspepsia, which often causes discomfort or pain after eating. In this study, researchers want to see if giving patients traditional dietary advice—like eating smaller meals and avoiding certain foods—helps them feel better compared to just reassuring them that their symptoms aren't caused by a serious illness. They will enroll 50 participants who meet specific criteria, such as having normal results from a recent stomach check and being able to read in English.

Participants in the trial will be randomly assigned to one of two groups: one will receive reassurance and information about their condition, while the other will get the same reassurance plus dietary advice. Over four weeks, they will fill out questionnaires to share how their symptoms improve. If you or someone you know is experiencing these symptoms and meets the eligibility criteria, this trial could provide valuable insights into managing functional dyspepsia.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Fulfil Rome IV symptoms criteria for functional dyspepsia
• • Normal upper gastrointestinal endoscopy within last 3 years
• • Online access
• • English literate
• Exclusion Criteria:
• • Organic gastrointestinal diseases (e.g. inflammatory bowel disease, GI cancer, coeliac disease)
• • Major abdominal surgery (except laparoscopy, appendectomy, cholecystectomy)
• • Documented H.pylori in the last 3 months
• • History of eating disorders
• • Body mass index \<20
• • Current use of opioids or anti-inflammatory drugs
• • Severe systemic disease (e.g. cardiac, renal, respiratory) necessitating frequent medical consultations
• • Pregnant
• • Diabetes mellitus
• • Scleroderma
• • Memory impairment
• • Current dietary interventions