Perpetual Observational Study - Ventilator Associated Pneumonia

Launched by EUROPEAN CLINICAL RESEARCH ALLIANCE FOR INFECTIOUS DISEASES (ECRAID) · Feb 7, 2023

Keywords

ClinConnect Summary

The Perpetual Observational Study on Ventilator-Associated Pneumonia (POS-VAP) is designed to better understand and prepare for future research on a serious lung infection that can occur in patients who are on mechanical ventilation in the Intensive Care Unit (ICU). This infection, called Ventilator-Associated Pneumonia (VAP), can lead to longer hospital stays, increased costs, and a higher risk of complications. The main goal of this study is to create a network of ICUs that can effectively conduct clinical trials to find ways to prevent or treat VAP.

To be eligible for this study, participants need to be at least 18 years old and expected to be on a ventilator for more than 48 hours while in the ICU. They must either give their own consent or have a legal representative provide consent on their behalf. Participants in this study will help researchers gather important information about VAP, which could lead to better treatments in the future. It's important to note that if a patient is not expected to recover during their hospital stay, they may not be eligible to participate.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • Age≥18 years
• * At risk of acquiring VAP during ICU stay, defined as:
• • Requiring admission or being admitted to the ICU.
• • Expected or documented to be under IMV for more than 48 hours.
• • Consent, either a written informed consent given by the study patient in full medical, psychological, cognitive, social or legal capacity to give an informed consent, or, if not possible, by a Legally Authorized Representative of the study patient OR any applicable locally accepted form of consent OR consent waiver allowing data collection and sharing of data according to ECRAID's principles
• Exclusion Criteria:
• • Death is deemed to be imminent or inevitable during this hospital admission AND one or more of the patient, substitute decision maker or attending physician are not committed to full active treatment.