Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer.

Launched by CENTRE HOSPITALIER DE L'UNIVERSITÉ DE MONTRÉAL (CHUM) · Jan 30, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how well a device called a Mandibular Advanced Device (MAD) can help patients with oropharyngeal cancer who also experience snoring and sleep apnea. Sleep apnea is a condition where a person's breathing stops and starts during sleep, and snoring can disturb both the person and their bed partner. The goal of the trial is to see if this device can improve sleep quality and overall comfort for these patients.

To participate in the study, individuals must be 18 years or older, have been diagnosed with oropharyngeal cancer, and have received radiation therapy. They should also be experiencing problems with snoring or breathing during sleep. However, certain people are not eligible, such as those who are pregnant, have severe depression, or are already using another treatment for sleep apnea. If you qualify and decide to join the study, you can expect to try out the MAD device and provide feedback on how it affects your sleep and comfort levels. This trial is currently recruiting participants, and it aims to provide valuable insights into managing sleep issues for cancer patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • oropharyngeal cancer diagnosis
• • 18 years of age and over
• • female or male; ratio of 1/4 toward men
• • had received RTH in the Department of Radiation Oncology,
• • reporting snoring and/or respiratory cessation complaints during sleep,
• Exclusion Criteria:
• • pregnant or breastfeeding woman;
• • edentation preventing retention of the oral appliance;
• • taking opioid or anxiolitic type medications;
• • history of major depression,
• • uncontrolled hypertension,
• • history of stroke;
• • under treatment with CPAP for sleep apnea;
• • regular and intense orofacial pain;
• • under pharmacological treatment for insomnia;
• • excessive alcohol or drug use (e.g., cannabis, opioid).