E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

Launched by NYU LANGONE HEALTH · Feb 9, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at two different ways to help people with Opioid Use Disorder (OUD) who also smoke cigarettes. The study aims to see if using electronic cigarettes (e-cigarettes) can help reduce smoking among these individuals, compared to a program that offers counseling and nicotine replacement therapy (NRT), which includes products like patches or gum. The trial is especially important because people with OUD often struggle with smoking, and finding effective ways to help them quit or reduce smoking can improve their overall health.

To participate in this study, you need to be at least 21 years old, currently smoke at least five cigarettes a day, and be in a treatment program for OUD (like methadone or buprenorphine) for at least 12 weeks. You should also be interested in reducing your cigarette smoking. If you join the trial, you can expect support and resources tailored to your needs, whether you choose the e-cigarette or counseling route. It's a great opportunity to explore new ways to improve your health while managing both opioid use and smoking.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Currently smokes 5 or more CPD
• • 2. Age ≥ 21 years
• • 3. Has a diagnosis of Opioid Use Disorder
• • 4. In OUDTP (buprenorphine or methadone) ≥ 12 weeks via self-report or EHR records
• • 5. Stable methadone or buprenorphine dose for two weeks via self-report or EHR records
• • 6. Interested in reducing combustible cigarette (CC) smoking but not necessarily trying to quit
• • 7. Own a mobile phone or have regular access to a mobile phone.
• • 8. Able to provide an additional contact to improve follow-up rates.
• Exclusion Criteria:
• • 1. Does not speak English or Spanish
• • 2. Are pregnant or breastfeeding
• • 3. Not able to provide consent
• • 4. Used tobacco products other than CC in the past 2 weeks (e.g., EC, cigarillo)
• • 5. Currently engaged in an attempt to quit CC smoking
• • 6. Reports having severe chronic obstructive pulmonary disease or asthma (i.e., with exacerbation requiring hospitalization or intubation in the prior 6 months)
• • 7. Reports current major depressive or manic episode, current psychotic disorder, past-year suicide attempt or psychiatric hospitalization, or current suicidal ideation with plan or intent.