Postprandial Glucose Levels, Gut Microbiota and Supplementation With Functional Foods in Adults

Launched by INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION SALVADOR ZUBIRAN · Feb 1, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating how certain foods can affect blood sugar levels after meals, and how our gut bacteria and urine might change in response to these foods. The study will last for 42 days and is divided into three parts: 14 days of no special diet, 14 days where participants will consume specific functional foods, and then another 14 days without the special foods again.

Adults aged 18 to 60 years who are generally healthy may be eligible to participate, but individuals with diabetes, high blood pressure, recent weight loss, or certain medical conditions will not qualify. Participants will need to provide informed consent and can expect to keep track of their blood sugar levels during the study. This trial aims to help us better understand the relationship between diet, gut health, and blood sugar control, which could lead to new insights for managing nutritional and metabolic health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male and female
• • Adults between 18 and 60 years of age.
• • The signing of the informed consent.
• Exclusion Criteria:
• • Patients with any type of diabetes.
• • Patients with high blood pressure.
• • Patients with acquired diseases secondarily producing obesity and diabetes.
• • Patients who have suffered a cardiovascular event.
• • Patients with gastrointestinal diseases.
• • Weight loss \> 3 kg in the last 3 months.
• • Catabolic diseases such as cancer and acquired immunodeficiency syndrome.
• • Pregnancy status.
• * Drug treatment:
• • Antihypertensive drugs or treatment (thiacycline, loop or potassium-sparing diuretics, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, alpha blockers, calcium antagonists, beta blockers).
• • Treatment with hypoglycemic agents (sulfonylureas, biguanides, incretins) or insulin and antidiabetic drugs.
• • Treatment with statins, fibrates or other drugs to control dyslipidemia.
• • Use of antibiotics in the three months prior to the study.
• • Use of steroid drugs, chemotherapy, immunosuppressants, or radiation therapy.
• • Anorexigenic or that accelerate weight loss such as sibutramine or orlistat.
• • Supplements with any of the functional foods used in the study.
• • Probiotic, prebiotic or symbiotic supplements.