Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical Application

Launched by CLINIQUES UNIVERSITAIRES SAINT-LUC- UNIVERSITÉ CATHOLIQUE DE LOUVAIN · Feb 1, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new non-invasive MRI technique called arterial spin labeling (ASL) to measure blood flow in the eye, specifically in patients with certain retinal diseases. The goal is to see how well this technology can assess the health of the retina by accurately measuring blood flow without needing any injections. Researchers want to ensure that the MRI process is reliable and precise before it can be widely used in clinical settings.

To participate in the study, you should be between 65 and 74 years old and have specific eye conditions like TAO optic neuropathy, inflammatory optic neuropathy, or ischemic optic neuropathy. It's important that you do not have any heart disease risk factors or other serious eye problems and that you can undergo an MRI safely. Participants will undergo MRI scans, and they should feel comfortable reading the study information and signing a consent form. If you are interested, this study could help improve how we understand and treat eye diseases related to blood flow.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • Carrier of target pathologies: TAO optic neuropathy, inflammatory optic neuropathy, ischemic optic neuropathy.
• • no cardiovascular risk factors or other ophthalmological pathology
• • adhere to the study protocol after reading the patient information document
• • signe the informed consent form to participate in the study
• • do not have any contraindications to an MRI examination
• • Exclusion criteria
• • Usual contraindications to MRI (Pacemaker, Metallic foreign body, Cochlear implant,...)
• • Severe claustrophobia