Fluorescence Laparoscopic Navigation for Rectal Cancer and Sigmoid Colon Cancer

Launched by CANCER INSTITUTE AND HOSPITAL, CHINESE ACADEMY OF MEDICAL SCIENCES · Feb 7, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at a new surgical technique called fluorescence laparoscopic navigation to help doctors remove lymph nodes in patients with colorectal cancer. The goal is to see how well this technique works compared to a standard method. It aims to understand both the short-term and long-term results of this surgery, specifically focusing on patients with rectal and sigmoid colon cancer.

To participate in this trial, you need to be between 18 and 75 years old and have a confirmed diagnosis of colorectal cancer. The tumor should be in a suitable location, and you should not have had any serious complications before surgery. If you're interested in joining, it's important to note that the trial is not yet recruiting participants, so you will need to wait until it starts. If you qualify, you can expect to receive specialized care during your surgery, and the results will help improve future treatments for others with similar conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participants are aged 18-75;
• • Colonoscopy biopsy confirms colorectal adenocarcinoma;
• • Colonoscopy shows that the lower edge of the tumor is located more than 10 cm from the margin or the tumor is located in the upper rectum and sigmoid colon by imaging diagnosis;
• • The tumor is staged cT1-4aNxM0 by preoperative imaging;
• • Participants have no local complications before surgery.
• Exclusion Criteria:
• • Previous history of malignant colorectal tumor;
• • Multiple primary colorectal tumors;
• • Preoperative imaging reveals suspicious positive lymph nodes in the submesenteric artery root region (area 253);
• • Patients undergoing neoadjuvant therapy before surgery;
• • With contraindications to laparoscopic surgery;
• • Histoty of multiple abdominal and pelvic surgery or extensive abdominal adhesions;
• • Other malignancies were diagnosed within the past 5 years;
• • History of severe mental illness;
• • Pregnant or lactating women;
• • With uncontrolled infection before surgery.