Long Term Cardiovascular Disease Event Risk for Patients Undergoing Major Non-Cardiac Surgery

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Feb 8, 2023

Keywords

ClinConnect Summary

This clinical trial is looking to understand how making healthy lifestyle choices around the time of surgery can affect a person's long-term risk of developing heart-related conditions. Researchers will observe patients for one month before their surgery and three months after to see if these choices, like eating well and staying active, can help lower the chances of heart disease in the future.

To be eligible for the study, participants need to be between 45 and 75 years old and scheduled for certain types of non-heart surgeries that are considered to have a medium to high risk. They should also have at least two risk factors for heart disease, such as high blood pressure or diabetes. If you join the study, you'll be monitored closely during the month leading up to your surgery and for three months afterward to track your health and lifestyle changes. This research could help improve understanding of how lifestyle affects heart health in patients undergoing surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 45 - 75 years
• • Scheduled for intermediate- to high risk non-cardiac surgery (intra-thoracic or intra-abdominal surgery, all vascular surgery, intra-cranial neurosurgery, spine surgery)
• • Expected post-operative length of stay of at least two days, according to the surgeon's expectation
• * At least two of the following CVD risk factors:
• • History of: Hypertension, Diabetes, Coronary artery disease, Chronic heart failure, Chronic kidney disease, Cerebrovascular disease, Peripheral vascular disease.
• • Obesity (BMI \>25 kg/m2), Current smoking, Poor exercise capacity (\<4 METS)
• Exclusion Criteria:
• • Currently participating in a CVD risk reduction program
• • Patient is scheduled to undergo transplant or has undergone emergency surgery
• • Life expectancy \<1 year (palliative surgery)
• • Recent (\<6 months) myocardial infarction or stroke
• • Surgery scheduled \<1 month
• • Inability to effectively communicate