Longitudinal Study for Central Nervous System Vasculitis
Launched by UNIVERSITY OF PENNSYLVANIA · Feb 8, 2023
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a serious condition called primary central nervous system vasculitis (CNSV), which can cause a variety of neurological problems, including strokes, memory issues, and even loss of vision. The goal of the study is to gather information about how this disease develops, how it can be treated, and what outcomes patients experience. Researchers are currently looking for participants who are at least 18 years old and have been diagnosed with CNSV. To be eligible, individuals must show specific signs of the disease and should not have other conditions that could explain their symptoms.
Participants in this study can expect to undergo evaluations that will help researchers better understand CNSV. This may involve tests and assessments related to their neurological health. It’s important to note that participants will need to agree to join the study by signing an informed consent form. This trial is open to anyone regardless of gender, and it aims to improve the understanding of CNSV to help future patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • i. Diagnostic criteria for CNSV
- • 1. The presence of an acquired and otherwise unexplained neurologic deficit
- • 2. The presence of either classic angiographic or histopathologic features of angiitis in the CNS
- • 3. No evidence of systemic vasculitis or any condition that could cause the angiographic or pathologic features
- • ii. ≥18 years of age
- Exclusion Criteria:
- • i. Unwilling to sign informed consent.
About University Of Pennsylvania
The University of Pennsylvania, a prestigious Ivy League institution located in Philadelphia, is renowned for its commitment to advancing medical research and improving healthcare outcomes. As a clinical trial sponsor, the university leverages its extensive resources, interdisciplinary expertise, and cutting-edge facilities to conduct innovative studies across various therapeutic areas. With a focus on translating scientific discoveries into clinical applications, the University of Pennsylvania fosters collaborations among leading researchers, clinicians, and industry partners, ensuring rigorous trial design and adherence to ethical standards. Through its dedication to excellence in research and education, the university plays a pivotal role in shaping the future of medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Philadelphia, Pennsylvania, United States
Nashville, Tennessee, United States
Cleveland, Ohio, United States
Hamilton, , Canada
Toronto, , Canada
Patients applied
Trial Officials
Rula Hajj-Ali, MD
Principal Investigator
The Cleveland Clinic
Leonard Calabrese, MD
Principal Investigator
The Cleveland Clinic
Peter Merkel, MD
Principal Investigator
University of Pennsylvania
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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