Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation

Launched by UNIVERSITY OF ILLINOIS AT CHICAGO · Feb 9, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how different sedation medications affect patients undergoing awake fiberoptic intubation, a procedure used to help people with difficult airways breathe more easily. The researchers want to compare the standard sedation drugs, midazolam and fentanyl, with a new option called dexmedetomidine. They believe that dexmedetomidine may be safer because it might not slow down breathing as much as the other medications. Participants in the study will receive either dexmedetomidine or a placebo (which is just a salt solution with no active drug) during their procedure.

To be eligible for this trial, patients must be identified as having potentially difficult airways and require the awake fiberoptic intubation procedure. If you qualify, you can expect to receive one of the sedation options during your procedure. The study is currently recruiting participants aged 65 to 74, and it is open to all genders. The goal is to find out which sedation method is the best for keeping patients comfortable and safe during this important procedure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Subjects with potentially difficult airways who require awake fiberoptic intubations will be identified from the OR schedule and the pre-operative clinic workups.
• Exclusion Criteria:
• • Anyone who does not meet the inclusion criteria