Optimizing PrEP Uptake and Adherence Among Male Sex Workers

Launched by BROWN UNIVERSITY · Feb 8, 2023

Keywords

ClinConnect Summary

The "PrEPare for Work" clinical trial is studying how to help male sex workers use and stick with a medication called PrEP, which is designed to prevent HIV. This trial aims to improve the ways we support these men in taking PrEP consistently, especially if they have engaged in unprotected anal sex and may be at risk for HIV. The study is currently looking for participants who are at least 18 years old, identify as male, have had condomless sex with another man in the past three months, and have exchanged sex for money or other valuable items. They should also be HIV negative or unsure of their status and not currently taking PrEP.

If you join the study, you will receive personalized support to help you understand and use PrEP effectively. Participants will also have the chance to contribute to important research that can improve health care for male sex workers in the future. It's important to know that individuals with certain health conditions or severe mental health issues may not be eligible to participate in this trial. If you're interested or think you might qualify, consider talking to a healthcare provider for more information.

Gender

MALE

Eligibility criteria

• • Inclusion
• • Age: 18 years or older
• • Assigned male sex at birth
• • Identifies as male at enrollment
• • Report having engaged in condomless anal sex with another man in the past 3 months
• • Report having exchanged sex for money, drugs, items of value, or a place to stay with another man in the past 3 months
• • Report HIV status as negative or unsure
• • Not currently on PrEP
• • Able to understand and speak English or Spanish
• • Exclusion
• • Unable to provide informed consent due to severe mental or physical illness, cognitive impairment, or substance intoxication at the time of interview (will use an adapted version of the Evaluation to Sign Consent Form65 to assess capacity)
• • Discovery of active suicidal ideation or major mental illness (e.g. untreated psychosis or mania) at the time of interview (these patients will be referred immediately for treatment)
• • Laboratory or clinical findings that would preclude PrEP initiation (e.g. Chronic Hepatitis B Virus infection, decreased creatinine clearance)
• • Participated in the pilot RCT and initiated PrEP during study participation