Lung Ultrasound Guided Choice of Best Positive End-Expiratory Pressure in Neonatal Anesthesia

Launched by VITTORE BUZZI CHILDREN'S HOSPITAL · Feb 18, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating a method to improve breathing support for newborns undergoing surgery. Specifically, the researchers want to see if using a special tool called Lung Ultrasound (LUS) can help doctors choose the best level of Positive End-Expiratory Pressure (PEEP) during anesthesia. PEEP is a technique used to keep the lungs open and working properly. The goal is to see if this method can reduce the amount of oxygen needed while still keeping oxygen levels in the blood stable, which may help prevent breathing complications after surgery.

To be eligible for this study, babies must be at least 33 weeks old at birth and up to 50 weeks old after conception, and they should be scheduled for surgery that requires general anesthesia. Babies with certain heart or lung conditions, immune diseases, or genetic issues, as well as those who do not have parental consent, cannot participate. If your baby is part of this trial, you can expect close monitoring and care to ensure the best possible outcomes during and after the surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients born after 33 weeks of gestationand up to the age of 50 post-conceptional weeks undergoing elective or urgent surgery requiring general anesthesia with endotracheal intubation
• Exclusion Criteria:
• • born at less than 33 weeks of gestation
• • patients with signs or symptoms of cardiac or lung abnormalities or diseases
• • patients with suspected/confirmed immune diseases, known or suspected metabolic or genetic conditions
• • no parental consent is obtained