Multi-Center Registry Cohort Study on Prognostic Factors and Prediction Model Construction in Aneurysmal SAH

Launched by SECOND AFFILIATED HOSPITAL OF NANCHANG UNIVERSITY · Feb 20, 2023

Keywords

ClinConnect Summary

The PROSAH-MPC study is a research project that aims to understand how patients with aneurysmal subarachnoid hemorrhage (aSAH) can be better treated and cared for. This condition occurs when there is bleeding in the space around the brain due to a burst blood vessel (aneurysm). The study is looking at various factors that can help predict how well patients will recover, including the chances of complications or disability. By gathering information from multiple hospitals across China, researchers hope to create more accurate tools for doctors to use in predicting patient outcomes.

To participate in the study, patients must have a confirmed diagnosis of aSAH and the cause must be identified as a ruptured aneurysm. They need to have undergone specific medical tests and treatments within a short time after their symptoms started. The study is currently recruiting participants, and anyone who meets these criteria, regardless of gender, between the ages of 65 and 74, may be eligible. For those who join, they can expect to contribute to important research that could improve future care for people with this serious condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Subarachnoid hemorrhage confirmed by computed tomography (CT);
• • Cerebral angiography (CTA) and digital subtraction angiography (DSA) examination confirming intracranial aneurysm rupture as the cause of the subarachnoid hemorrhage;
• • Blood routine, biochemical function, blood coagulation function, and craniocerebral CT performed within 24 hours of symptom onset;
• • Underwent aneurysm clipping by surgery or endovascular embolization within 72 hours after-onset.
• Exclusion Criteria:
• • Aneurysm rupture bleeding time exceeding 24 hours before hospital admission;
• • Incomplete image data or blood test information;
• • Long-term use of anticoagulant medications such as aspirin or warfarin;
• • Admitted to hospital with active infectious diseases;
• • long-term anticoagulant drugs such as aspirin, wave dimensions;
• • Presence of other intracranial vascular malformations.