Radial Forearm Donor Site Closure

Launched by UNIVERSITY OF BRITISH COLUMBIA · Feb 21, 2023

Keywords

ClinConnect Summary

This clinical trial is studying two different methods for closing the donor site after a surgical procedure called radial forearm free flap (RFFF), which is commonly used to help reconstruct the mouth and throat area for patients with oral cancer. The trial aims to find out whether patients who receive a skin graft taken from their thigh (called a split-thickness skin graft) have better results in terms of how the area looks and functions compared to those who have a local flap closure (known as a hatchet flap) from the same arm.

To participate in this trial, you need to be an adult aged 18 or older who has oral cavity disease that requires this type of reconstruction. Unfortunately, individuals with serious medical conditions or those who have past injuries affecting the use of both hands cannot take part. If you join the trial, you can expect to receive one of the two closure methods and will complete some questionnaires after your surgery to help researchers assess your recovery and satisfaction with the results. The trial is currently recruiting participants, and it’s open to everyone regardless of gender.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults aged 18 or older
• • Oral cavity disease (malignant or benign) requiring radial forearm free flap reconstruction
• Exclusion Criteria:
• • Serious medical comorbidities including metastatic disease or other contraindications to surgery
• • Any pre-existing condition affecting the use of both hands, including previous major scars
• • Unable or unwilling to complete post-operative questionnaires in English
• • Pregnant or lactating women