3D Specimen Maps for RT Planning

Launched by VANDERBILT UNIVERSITY MEDICAL CENTER · Feb 14, 2023

Keywords

ClinConnect Summary

This clinical trial, titled "3D Specimen Maps for RT Planning," is studying how using special 3D maps of a patient's tumor can help doctors plan better radiation therapy for people with head and neck cancer. The goal is to see if these maps can improve the way radiation is targeted to the cancer while protecting important nearby organs. All participants will still receive the usual radiation treatment after their surgery, but researchers want to find out if these detailed maps can help doctors communicate better with each other about the patient's care.

To take part in this study, patients must be over 18 years old and have been diagnosed with head and neck cancer that has been confirmed by a biopsy. They should have already had surgery to remove the tumor and need to receive radiation therapy afterward. Participants will be treated at one of the Vanderbilt locations in Nashville, Franklin, or Lebanon. It's important for potential participants to know that this trial is currently looking for volunteers, and their involvement will help improve cancer treatment for others in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Over the age of 18
• • 2. Biopsy-confirmed mucosal head and neck cancer. All histologic malignancies will be included.
• 3. Patients who have completed primary tumor surgical resection in the following anatomic subsites:
• • 1. oral cavity (oral tongue, floor of mouth, hard palate, buccal mucosa, retromolar trigone, maxillary and mandibular alveolus, lip)
• • 2. oropharynx (soft palate, base of tongue, palatine tonsils)
• • 3. hypopharynx (piriform sinus, post-cricoid, posterior pharyngeal wall)
• • 4. larynx (supraglottic, glottic, subglottic);
• • 4. Patients who have consented to 3D specimen mapping on protocol IRB # 221597 and for whom 3D specimen maps are therefore available.
• • 5. Patients are indicated to receive curative-intent post-operative radiotherapy and intend to receive radiotherapy at Vanderbilt University Medical Center or Vanderbilt Ingram Cancer Center sites in Nashville, Franklin, or Lebanon
• Exclusion Criteria:
• • 1. Under the age of 18
• • 2. Cutaneous malignancies
• • 3. Characteristics that make the process of informed consent questionable
• • 4. Pregnant women
• • 5. Patients with contraindications to radiotherapy