The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Launched by UNIVERSITY OF SOUTHERN CALIFORNIA · Feb 22, 2023

Keywords

ClinConnect Summary

This clinical trial is studying whether a medication called zolpidem can help improve the recovery and overall experience for patients after they have surgery to fuse parts of their lower spine. The researchers want to see if taking zolpidem around the time of the surgery makes a difference in how patients feel and recover afterward. This trial is currently recruiting participants who are between the ages of 18 and 75 and have specific conditions related to their lumbar spine, such as degeneration or pain.

To be eligible for this study, participants must be planning to undergo a certain type of spine surgery called a lumbar fusion, where doctors join together one to three levels of the spine. However, people who regularly use sleep aids, have certain sleep disorders, or have had previous spine surgeries are not able to participate. If you join the study, you can expect to be monitored closely during your recovery, and your experiences and outcomes will be assessed to help researchers understand the effects of zolpidem. This trial is important because it could lead to better ways to manage recovery after spine surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • degenerative lumbar disease
• • age of 18-75
• • undergoing open primary one- to three-level lumbar fusion
• Exclusion Criteria:
• • currently use a sleep aid nightly
• • diagnosed with insomnia or sleep apnea
• • history of delirium with opiates or zolpidem
• • allergic to opiates or zolpidem
• • had previous lumbar spine surgery
• • undergoing minimally invasive lumbar fusion,
• • undergoing lumbar fusion for fracture, infection, tumor, or an inflammatory spondyloarthropathy