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Search / Trial NCT05746247

Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics

Launched by UNIVERSITY OF PENNSYLVANIA · Feb 17, 2023

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Machine Learning Find Fh

ClinConnect Summary

Phase 1:

Aim 1: Adjusting and refining the application of the FIND FH tool to the UPHS EHR database Aim 2: Identifying the barriers and facilitators to making a diagnosis of FH and initiating or intensifying therapy for individuals with FH through qualitative interviews with clinicians and patients and creating a behavioral roadmap to inform the implementation approaches to test in the pilots

Phase 2:

Aim 1: Co-design implementation strategies using behavioral economics in partnership with the Family Heart Foundation Aim 2: Pilot implementation strategies with an enrollment goal of 80 pa...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Must be a patient at Penn Medicine
  • Must have been flagged by the FIND FH tool as having a high probability of FH
  • First language is English
  • Resides in PA or NJ
  • Exclusion Criteria:
  • Already have been clinically diagnosed with FH using the proper ICD-10 code
  • Currently see a lipid specialist at Penn Medicine
  • Pass study clinician's Study Validity Check

About University Of Pennsylvania

The University of Pennsylvania, a prestigious Ivy League institution located in Philadelphia, is renowned for its commitment to advancing medical research and improving healthcare outcomes. As a clinical trial sponsor, the university leverages its extensive resources, interdisciplinary expertise, and cutting-edge facilities to conduct innovative studies across various therapeutic areas. With a focus on translating scientific discoveries into clinical applications, the University of Pennsylvania fosters collaborations among leading researchers, clinicians, and industry partners, ensuring rigorous trial design and adherence to ethical standards. Through its dedication to excellence in research and education, the university plays a pivotal role in shaping the future of medicine.

Locations

Philadelphia, Pennsylvania, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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