The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy
Launched by DHAKA MEDICAL COLLEGE · Feb 24, 2023
Trial Information
Current as of July 22, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This prospective hospital based open label interventional study will be conducted in Dhaka Medical College Hospital, Dhaka after receiving approval of this protocol from ethical review committee of DMC. Patients who match the inclusion and exclusion criteria will be enrolled in the study by simple random sampling. A written informed consent will be taken from patients or from their legal attendants after describing the aim, purpose and procedure of the study. Focal epilepsy will be diagnosed according to the criteria of the Commission on Classification and Terminology of the International L...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age \> 18 years regardless of gender.
- • Newly diagnosed focal epilepsy patient with or without secondary generalization.
- • Relapse following antiepileptic drug withdrawal or failure on treatment other than lamotrigine or carbamazepine.
- • Willing to participate and give informed written consent.
- Exclusion Criteria:
- • Patient with generalized seizure.
- • Cryptogenic or unknown onset seizure.
- • Known hypersensitivity to medication.
- • History of drug abuse.
- • Patient with serious medical conditions such as cardiovascular diseases, hepatic failure, renal failure, malignancy.
About Dhaka Medical College
Dhaka Medical College is a prestigious medical institution in Bangladesh, renowned for its commitment to advancing healthcare through rigorous research and clinical education. As a clinical trial sponsor, Dhaka Medical College provides a robust framework for conducting innovative research aimed at improving patient outcomes and enhancing medical knowledge. The institution is dedicated to upholding the highest ethical standards in clinical trials, ensuring participant safety, and fostering collaborations with local and international research entities. With a focus on evidence-based medicine, Dhaka Medical College actively contributes to the development of new therapies and treatment protocols, positioning itself as a leader in the medical research community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Dhaka, , Bangladesh
Patients applied
Trial Officials
Dr Mohammad Osman, MBBS
Principal Investigator
MD Neurology Thesis
Kazi Gias Uddin Ahmed, MD
Study Chair
Associate professor, Dhaka Medical College
Reaz mahmud
Study Director
Dhaka Medical College
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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