A-LiNK: Improving Outcomes in Autoimmune Liver Disease
Launched by CHILDREN'S HOSPITAL MEDICAL CENTER, CINCINNATI · Feb 28, 2023
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
The A-LiNK trial is focused on improving care for children with autoimmune liver diseases, specifically Autoimmune Hepatitis (AIH) and Primary Sclerosing Cholangitis (PSC). The goal of this study is to create a network where different medical centers can share information and learn from each other to provide better treatment options. By gathering data on patient outcomes and treatment processes, the trial aims to develop better guidelines for managing these conditions, which can be complex and vary widely from one patient to another.
To participate in this trial, children must have a clinical diagnosis of AIH, PSC, or autoimmune sclerosing cholangitis (ASC) but cannot have a history of liver transplant. If eligible, participants can expect to be part of a system that prioritizes their needs and experiences, helping researchers and doctors understand how to improve health outcomes and quality of life for kids with these liver diseases. The study is currently recruiting participants, and it welcomes children of any gender within the age range specified.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Clinical diagnosis of autoimmune hepatitis (AIH)
- • Clinical diagnosis of primary sclerosing cholangitis (PSC)
- • Clinical diagnosis of autoimmune sclerosing cholangitis (ASC)
- Exclusion Criteria:
- • • History of liver transplant
About Children's Hospital Medical Center, Cincinnati
Children's Hospital Medical Center in Cincinnati is a leading pediatric healthcare institution dedicated to advancing child health through innovative clinical research and comprehensive patient care. Renowned for its commitment to excellence, the center conducts a wide range of clinical trials aimed at developing and evaluating new treatments and therapies for pediatric populations. With a focus on multidisciplinary collaboration and ethical research practices, Children's Hospital Medical Center strives to improve health outcomes for children while contributing to the broader scientific understanding of pediatric medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Saint Louis, Missouri, United States
Cincinnati, Ohio, United States
Palo Alto, California, United States
Columbus, Ohio, United States
Seattle, Washington, United States
Dallas, Texas, United States
Pittsburgh, Pennsylvania, United States
Indianapolis, Indiana, United States
Patients applied
Trial Officials
Amy E Taylor, MD
Principal Investigator
Children's Hospital Medical Center, Cincinnati
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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