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Search / Trial NCT05750667

Penn Family Screening for Familial Hypercholesterolemia

Launched by NORTHWESTERN UNIVERSITY · Feb 27, 2023

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Implementation Science Behavioral Economics Equity Cascade Screening

ClinConnect Summary

This project leverages Penn Medicine's and the investigative team's longstanding partnership with the Family Heart Foundation (FHF), a nonprofit research and advocacy organization, to test two promising approaches to implementing cascade screening. The study will test two patient-facing implementation strategies to increase reach of cascade screening with FH probands within Penn Medicine. This pragmatic randomized controlled trial (RCT) will test (a) a health system (Penn Medicine)-mediated strategy using automated text messages and emails, (b) an FHF-mediated strategy delivered by a naviga...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria (probands):
  • Adults aged 18 years and older with clinically diagnosed FH who are treated within the Penn Medicine system
  • Have contact information for at least one living, first-degree biological relative
  • Have a cell phone with texting capabilities and/or access to email
  • Exclusion Criteria (probands):
  • People under age 18
  • Do not have contact information for at least one living, first-degree biological relative
  • Do not have a cell phone with texting capabilities nor access to email

About Northwestern University

Northwestern University is a prestigious academic institution renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a robust infrastructure that supports interdisciplinary collaboration, Northwestern leverages its expertise in various fields, including medicine, engineering, and social sciences, to drive groundbreaking studies. The university is dedicated to adhering to the highest ethical standards and regulatory compliance, ensuring that all clinical trials are conducted with the utmost integrity and focus on participant safety. Through its Clinical Trials Office, Northwestern aims to translate scientific discoveries into effective therapies, ultimately enhancing health outcomes and contributing to the broader medical community.

Locations

Philadelphia, Pennsylvania, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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