Gastrointestinal Stimulation As a Treatment of Postoperative Ileus Following Extensive Surgery

Launched by UNIVERSITY OF AARHUS · Feb 21, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to help patients who experience bowel paralysis after having major surgery for certain types of cancer, like colorectal or appendiceal cancer. The researchers want to see if using a special device called a pacemaker to stimulate the gastrointestinal tract can help reduce the time it takes for the bowel to start working again after surgery. Participants will have this pacemaker attached during their surgery, and it will either be turned on or off to compare the results.

To be eligible for this trial, participants should be adults over 18 who are scheduled for specific types of cancer surgeries. They should be able to give informed consent and not have any significant previous surgeries or medical devices implanted that could interfere with the trial. After surgery, participants will take a small capsule that tracks how well their digestive system is working and will also keep a daily diary of their bowel movements to help the researchers understand the effects of the treatment. This trial is currently recruiting participants of all genders aged 65 and older.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients planned for elective cytoreductive surgery with or without heated intraperitoneal chemotherapy due to either colorectal or appendiceal cancer or with peritoneal metastases or due to pseudomyxoma peritonei
• • Written and orally informed consent
• • Over 18 years of age
• Exclusion Criteria:
• • Previous upper gastric or esophageal resection
• • History of difficulties in swallowing or gastrointestinal stenosis
• • Implanted or portable electrical medical device e.g. cardiac pacemaker, defibrillator or infusion pump etc.
• • Pregnant or breast-feeding women