Effect of Fecal Microbiota Transplantation (FMT) in Pediatric Functional Gastrointestinal Disorders

Launched by BIAO ZOU · Feb 22, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called Fecal Microbiota Transplantation (FMT) for children with Functional Gastrointestinal Disorders (FGIDs). FGIDs can cause symptoms like stomach pain and discomfort without any clear physical causes. The researchers want to see if FMT, which involves transferring healthy bacteria from a donor's stool to help restore a balanced gut environment, is safe and effective for pediatric patients.

To participate, children aged 1 to 15 years old (365 to 5478 days old) who have been diagnosed with FGIDs according to specific guidelines (the ROME IV criteria) may be eligible. However, children with other serious gastrointestinal diseases or chronic health issues, as well as those who are not growing well, will not be included. If enrolled, participants will receive the FMT treatment and will be monitored to understand how well it works and if there are any side effects. This trial is currently looking for volunteers, so families interested in this treatment option can consider joining.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The diagnosis and classification of patients with FGIDs were in accordance with the ROME IV criteria for children
• Exclusion Criteria:
• • organic gastrointestinal disease (as established by medical history, blood routine, biochemistry, c-reaction protein, erythrocyte sedimentation rate, and fecal routine examinations.)
• • other chronic disease
• • growth failure