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Search / Trial NCT05755672

On-treatment Biomarkers in Metastatic Colorectal Cancer for Life

Launched by REGION SKANE · Mar 2, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Metastatic Colorectal Cancer Chemotherapy Targeted Therapy Tumor Heterogeneity Tumor Evolution

ClinConnect Summary

The On-CALL study is a research trial designed to better understand how metastatic colorectal cancer (mCRC) changes during treatment. It aims to find out why some patients do not respond well to therapy, despite advances in cancer treatments. The study will involve patients diagnosed with mCRC who are starting treatment with the goal of curing their cancer at Skåne University Hospital. Researchers will collect detailed information about each patient's cancer and take blood samples at different times to analyze how the cancer evolves over the course of treatment.

To be eligible for this study, participants must be adults aged 40 to 76 who have been diagnosed with synchronous mCRC and are willing to participate in the study. Patients who do not agree to the study terms or fall outside the age range will not be able to join. Those who participate can expect to provide tissue and blood samples, which will help researchers understand how the cancer develops and may lead to more personalized treatment options in the future. This study is currently recruiting participants, and all genders are welcome to join.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinical diagnosis of synchronous metastatic colorectal cancer, planned cancer treatment with curative intent at the Skåne University Hospital
  • Exclusion Criteria:
  • Not accepting the study inclusion terms (informed consent not obtained)
  • Age below or above the age limit

About Region Skane

Region Skåne is a leading healthcare authority in Sweden, dedicated to advancing medical research and improving patient care through innovative clinical trials. Committed to fostering collaboration between researchers, healthcare professionals, and patients, Region Skåne aims to enhance the understanding of various health conditions and develop effective treatment strategies. With a focus on ethical standards and patient safety, the organization plays a pivotal role in shaping the future of healthcare in the region and beyond, ensuring that clinical trials are conducted with the highest level of scientific rigor and transparency.

Locations

Lund, Skåne, Sweden

Malmö, Skåne, Sweden

Lund, Skåne, Sweden

Malmö, Skåne, Sweden

Lund, , Sweden

Malmö, , Sweden

Patients applied

0 patients applied

Trial Officials

Karin Jirström, M.D. PhD.

Study Director

Region Skåne

Jakob Eberhard, M.D. PhD.

Study Chair

Region Skåne

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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