Unusual Infiltrative Patterns of Malignant Cells in Endometrial Carcinoma and Immunohistochemical Expression of P53

Launched by ASSIUT UNIVERSITY · Feb 23, 2023

Keywords

ClinConnect Summary

This clinical trial is studying different patterns of cancer cell growth in women with endometrial cancer, which is cancer that starts in the lining of the uterus. The researchers want to understand how these unique patterns relate to patient outcomes, such as how long someone lives without their cancer returning. They are also looking at the role of a specific protein called P53, which may help provide important information about the cancer’s behavior.

To participate in this study, women must have a confirmed diagnosis of endometrial cancer and have had a total abdominal hysterectomy, meaning they have had their uterus surgically removed. However, the study will not include women who have had certain types of biopsies, prior treatments like chemotherapy or radiation, or those with different kinds of cancer. The trial is not yet recruiting participants, and further details about what participants can expect will be provided once it begins.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Histologically proven Endometrial cancer specimens.
• • 2. underwent total abdominal hysterectomy, with myometrial invasion.
• Exclusion Criteria:
• • 1. Endometrial biopsies
• • 2. hysterectomy specimens diagnosed with different pathological lesions rather than EC.
• • 3. Specimens with prior chemotherapy or radiotherapy.
• • 4. specimens without myometrial invasion.