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Search / Trial NCT05756426

Consortium for Optimized Integration of Bio-Artificial Blood Components for Adaptive Resuscitation Therapy

Launched by UNIVERSITY OF MARYLAND, BALTIMORE · Feb 23, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Hemostasis Vasoactivity Oxygen Affinity Red Blood Cell Whole Blood Analogue Perfusion Nitric Oxide Methemoglobin

ClinConnect Summary

This clinical trial is studying a new type of artificial blood that could help save lives in emergencies when regular blood is not available or suitable. The goal is to create a product that works like whole blood by combining different artificial components that mimic the functions of oxygen carriers, plasma, and platelets. This new blood substitute aims to improve treatment for patients experiencing severe bleeding, whether in civilian situations like trauma or on the battlefield. By developing this product, researchers hope to provide better care during the critical time right after an injury.

To participate in this trial, you need to be at least 18 years old, weigh more than 88 pounds, and generally be in good health. Unfortunately, people with infections, pregnant individuals, or those who do not speak English are not eligible to join. If you decide to participate, you will help test the effectiveness of this artificial blood in a controlled setting, which could lead to better outcomes for patients facing life-threatening bleeding in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Subject \>/= 18 years of age
  • Subject weighs \>40kg (88lbs)
  • Subject must be generally healthy
  • Exclusion Criteria:
  • Suspected or diagnosed with ongoing (chronic) or acute infection
  • Subject is pregnant
  • Subject is non-english speaking

About University Of Maryland, Baltimore

The University of Maryland, Baltimore (UMB) is a leading academic institution dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, UMB leverages its extensive resources and expertise across various disciplines, including medicine, pharmacy, nursing, and social work, to contribute to groundbreaking discoveries and improve patient outcomes. Committed to ethical research practices and collaboration, UMB fosters an environment that promotes the translation of scientific knowledge into real-world applications, ultimately enhancing the well-being of diverse populations.

Locations

Baltimore, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Stephen Rogers, PhD

Principal Investigator

University of Maryland, Baltimore

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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