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Search / Trial NCT05762055

Prospective Comparative Analysis of ACDF vs Fusion Interbody Cages With nanoLOCK Osseointegrative Technology

Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Feb 27, 2023

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Spine Cervical Discectomy Bony Fusion Dysphagia Radiographic Fusion Radiographic Adjacent Segment Disease

ClinConnect Summary

Aim 1: Examine the effect of nanoLOCK technology on rates of postoperative dysphagia after ACDF.

Aim 2: Evaluate the effect of nanoLOCK technology on radiographic fusion.

Aim 3: Evaluate how nanoLOCK technology influences the development of radiographic adjacent segment disease.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Subjects 18 years of age or older
  • Subjects undergoing ACDF surgery for degenerative pathology (one, two or three levels)
  • Subjects with no prior history of cervical spine surgery
  • Subjects with complete/usable data
  • Exclusion Criteria:
  • Subjects under the age of 18
  • Subjects not undergoing ACDF surgery
  • Subjects with prior cervical spine surgery
  • Subjects with cervical neoplastic or infectious disease pathology
  • Subjects with cervical trauma pathology
  • ACDF performed at C2-3
  • Subjects with incomplete/unusable data

About University Of Texas Southwestern Medical Center

The University of Texas Southwestern Medical Center is a leading academic medical institution dedicated to advancing healthcare through innovative research, education, and clinical excellence. With a strong emphasis on translational medicine, the center conducts cutting-edge clinical trials aimed at developing novel therapies and improving patient outcomes across a wide range of diseases. Its multidisciplinary approach leverages a collaborative network of renowned faculty, state-of-the-art facilities, and a commitment to ethical research practices, positioning UT Southwestern at the forefront of medical discovery and patient care.

Locations

Dallas, Texas, United States

Patients applied

0 patients applied

Trial Officials

Salah Aoun, MD

Principal Investigator

UT Southwestern Medical Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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