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Search / Trial NCT05764213

Improving Maternal Mental Health & SUD Screening and Treatment

Launched by MEDICAL UNIVERSITY OF SOUTH CAROLINA · Mar 1, 2023

Trial Information

Current as of July 22, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

Aim 1: To determine differences in rates of treatment attendance and retention for Perinatal Mood and Anxiety Disorders (PMADs) and Perinatal Substance Use Disorders (PSUDs) between participants assigned to LTWP, compared to SBIRT.

Aim 2: To determine differences in Patient-Reported Outcomes (PROs) including depressive symptoms, quality of life, substance use, and maternal functioning and well-being measured at baseline and 2, 5, 8, and 11 months postpartum.

Gender

FEMALE

Eligibility criteria

  • Aim 1:
  • This study is a cluster RCT step wedge design so we are randomizing on the clinic level, not the individual level. The clinics are made up of 4 "wedges" (3 clinics/wedge). Pregnant women receiving prenatal care in these clinics will receive SBIRT as part of usual care. Clusters of clinics will be randomized to an LTWP start date where they will transition from SBIRT to LTWP for the purposes of screening and referral to treatment.
  • EHR Data Collection (PPP):
  • Inclusion:
  • 1. Age 18-45
  • 2. pregnant and entering prenatal care in one of MUSC's OB clinics
  • 3. attended a prenatal appointment at an MUSC clinic
  • Exclusion:
  • a.) primary language is not English or Spanish
  • Aim 2:
  • Study Assessments at baseline and 2, 5, 8, and 11 months postpartum (PPP):
  • Inclusion:
  • 1. Age 18-45 years
  • 2. pregnant
  • 3. attended an initial prenatal appointment at an MUSC OB clinic
  • Exclusion:
  • 1. Unable to complete study assessments
  • 2. primary language is not English or Spanish

About Medical University Of South Carolina

The Medical University of South Carolina (MUSC) is a leading academic health center dedicated to advancing medical research and improving patient care through innovative clinical trials. With a strong emphasis on translational medicine, MUSC leverages its extensive resources and expertise to facilitate groundbreaking studies across various medical disciplines. The institution is committed to fostering collaboration among researchers, healthcare professionals, and patients, ensuring that cutting-edge discoveries translate into effective treatments. As a pioneer in health education and research, MUSC plays a vital role in shaping the future of medicine and enhancing health outcomes in the community and beyond.

Locations

Charleston, South Carolina, United States

Patients applied

0 patients applied

Trial Officials

Constance Guille, MD

Principal Investigator

Medical University of South Carolina

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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