Hyperpolarized 129Xe MRI Lung Health Cohort

Launched by UNIVERSITY OF KANSAS MEDICAL CENTER · Mar 1, 2023

Keywords

ClinConnect Summary

The Hyperpolarized 129Xe MRI Lung Health Cohort trial is studying lung health in young adults who are part of the American Lung Association’s Lung Health Cohort. This trial aims to use a special type of imaging called Hyperpolarized 129Xe MRI to take detailed pictures of the lungs. By looking at these images, researchers hope to learn more about how healthy lungs work and to identify any early signs of lung problems that could lead to chronic lung diseases in the future.

To be eligible for this trial, participants need to be part of the Lung Health Cohort and have had a CT scan within the last two years. Unfortunately, individuals with certain medical devices like pacemakers or who are pregnant or breastfeeding cannot participate. If someone joins, they can expect to undergo the Hyperpolarized 129Xe MRI, which is a safe and non-invasive way to assess lung health. This research is important as it could help improve our understanding of lung conditions and lead to better prevention and treatment strategies in the long run.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Is enrolled in the American Lung Association Lung Health Cohort Study.
• • Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date.
• Exclusion Criteria:
• • Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, \> 140 cm shoulder circumference, dependent on weight distribution).
• • Is pregnant or breastfeeding
• • Oxygen saturation (SpO2) \<88% on room air or with supplemental oxygen.