Assessment of Left Ventricular Filling Pressure by Applying Artificial Intelligence Algorithms to Left Atrial Speckle-tracking Echocardiography

Launched by ISTITUTO AUXOLOGICO ITALIANO · Mar 3, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new software that uses artificial intelligence to help doctors estimate a specific heart measurement called left ventricular filling pressure (LVFP) without needing invasive procedures. The goal is to see if this software can accurately measure LVFP by looking at images of the heart taken with echocardiography, which is a safe and painless ultrasound test. Researchers will compare the results from this new software to traditional methods that involve more invasive techniques. They are particularly interested in how well this software can detect increased pressure in the heart, which can indicate heart failure.

To be eligible for this study, participants should be at least 18 years old and able to provide consent. They should not be pregnant and must have good quality images of their heart taken during the echocardiography. Some people may not qualify, such as those with certain heart conditions or those taking specific medications that could affect the study results. If you decide to participate, you can expect to have your heart examined using echocardiography, and you will be contributing to important research that could improve how doctors assess heart health in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ≥ 18 yo,
• • Signed informed consent to be part of this study,
• • No pregnancy,
• • Good acoustic window and patient cooperation to obtain good 2- and 3-dimensional datasets focused on left atrium (LA),
• Exclusion Criteria:
• • Unwillingness to be part of the study,
• • Patients with poor 2-dimensional imaging quality in ≥ 1 LA segment or lacking of a discernible R-R interval, which might preclude accurate strain measurements,
• • Patients with more than mild mitral valve heart disease, aortic regurgitation, left side valvular prosthesis or mitral valve repair, mitral annulus calcification (≥ 5 mm),
• • Patients with history or presence of atrial fibrillation (AF), supraventricular arrhythmias, ventricular paced rhythm, left bundle branch block (LBBB),
• • Patients taking diuretics or vasodilators (nitrates) on the day of the examination, which could alter loading conditions.