Implication of New High Resolution Ultrasonographic Modalities for Diagnosis of Fetal Nervous System Anomalies

Launched by WOMAN'S HEALTH UNIVERSITY HOSPITAL, EGYPT · Mar 5, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating how new ultrasound techniques can help doctors better diagnose problems with the fetal nervous system, particularly during the mid-pregnancy ultrasound scan. The study aims to evaluate the baby's brain and spine using advanced imaging methods to ensure that these important structures are developing normally. The ultrasound will look at specific areas of the brain and measure certain features to check for any abnormalities.

Women who are pregnant and have certain risk factors may be eligible to participate in this trial. This includes those whose routine ultrasounds have raised concerns about possible brain or spinal problems, those with a family history of such issues, or women who have had previous pregnancies affected by these conditions. Participants can expect to undergo detailed ultrasound imaging as part of their routine prenatal care. It's important to note that this study is focused on pregnancies that show some level of risk, so women with low-risk pregnancies will not be included.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Suspicion of CNS or spinal malformation at routine screening ultrasound Suspicion of CNS or spinal malformation at nuchal translucency scan Family history of inheritable CNS spinal malformations Previous pregnancy complicated by fetal brain or spinal malformation Fetus with congenital heart disease Monochorionic twins Suspected congenital intrauterine infection Exposure to teratogens known to affect neurogenesis
• Exclusion Criteria:
• • Low risk pregnancy