Characterization of Immune-response in Autoimmune Encephalitis and Paraneoplastic Neurological Syndromes

Launched by HOSPICES CIVILS DE LYON · Mar 6, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at two rare conditions called autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS), which affect the brain and nervous system. These conditions can cause a variety of symptoms, but they are difficult to diagnose because there are no specific signs that clearly point to them. The goal of this trial is to better understand how the immune system responds in patients with these conditions, particularly focusing on certain antibodies that can help in making a diagnosis and predicting how well patients will respond to treatment.

To participate in the trial, individuals must have a neurological disorder and can either have specific antibodies in their blood or spinal fluid or not. The trial is currently recruiting participants aged 65 and older, and both men and women are welcome to join. If you qualify, you can expect to undergo some tests to help researchers understand your immune response better. This information may help improve future treatments for AE and PNS and provide valuable insights into how to manage these challenging conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient with neurological disorder
• • Patient with antibodies or not in sera or CSF
• Exclusion Criteria:
• • - No available clinical data