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Search / Trial NCT05780775

Lipid Balance in Adult Sickle Cell Patients

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE LA GUADELOUPE · Mar 21, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Sickle Cell Disease Lipids Vasoocclusive Crisis Priapism Pulmonary Arterial Hypertension

ClinConnect Summary

This clinical trial, called "Lipid Balance in Adult Sickle Cell Patients," is studying how fat levels in the blood (lipid profiles) relate to complications of sickle cell disease in adults living in the French Caribbean. The researchers want to understand how these lipid levels change during and after serious events, like painful crises, and how they might differ from person to person over four years. They will also look at genetic factors that might influence these complications and measure things like insulin resistance and certain fat levels in the blood.

To be eligible for this study, you need to be at least 18 years old and diagnosed with either sickle cell anemia or SC sickle cell disease. You should live in Guadeloupe or Martinique and have been stable without any acute complications for the past month. If you choose to participate, you will help researchers gather important information that could improve understanding and treatment of sickle cell disease. It’s important to know that the study is currently recruiting participants, and you will need to provide consent after learning about the study in detail.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Aged from 18 years and over
  • Be affected with Sickle cell anemia or SC sickle cell
  • Living in French Caribbean Islands of Guadeloupe or Martinique and followed by physicians issued from a French West Indies Sickle Cell Reference or Competence Center
  • At steady state in the last month (without acute complication)
  • To have given a written consent after information on the study.
  • Exclusion Criteria:
  • Other hemoglobinopathies than sickle cell disease
  • Pregnancy or lactation
  • Patient under judicial protection or without freedom
  • Patient not affiliated with a social security system
  • Patient hospitalized for transfusion or bleeding in the last 3 months

About Centre Hospitalier Universitaire De La Guadeloupe

The Centre Hospitalier Universitaire de la Guadeloupe (CHUG) is a prominent academic medical center dedicated to advancing healthcare through innovative research and clinical trials. Located in the French overseas department of Guadeloupe, CHUG combines cutting-edge medical practices with a commitment to improving patient outcomes across diverse populations. As a leading institution in the Caribbean region, CHUG collaborates with multidisciplinary teams to conduct rigorous clinical studies aimed at enhancing treatment protocols and contributing to medical knowledge. The center emphasizes ethical standards and patient safety, fostering an environment that supports both scientific inquiry and community health advancement.

Locations

Pointe à Pitre, Guadeloupe, France

Le Lamentin, Martinique, France

Patients applied

0 patients applied

Trial Officials

Marie-Laure LALANNE-MISTRIH

Principal Investigator

: University Hospital of Guadeloupe - Department of Nutrition

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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