Hysteroscopy vs. Endouterine Aspiration in the Management of Trophoblastic Retention

Launched by UNIVERSITY HOSPITAL, MONTPELLIER · Mar 16, 2023

Keywords

ClinConnect Summary

This clinical trial is studying two different methods for treating a condition called trophoblastic retention, which can occur after an early miscarriage. In this situation, some tissue from the pregnancy remains in the uterus, and it can sometimes lead to ongoing bleeding and emotional distress. The trial aims to compare the effectiveness of two treatment options: hysteroscopy (a procedure that allows doctors to look inside the uterus and remove tissue) and endo-uterine aspiration (a method that gently suctions out the remaining tissue).

To participate in this trial, women who have had a spontaneous miscarriage and are experiencing this condition may be eligible. Key criteria for joining include being diagnosed with retained tissue through an ultrasound and wanting surgical treatment. Participants will be randomly assigned to one of the two treatment groups and can expect follow-up assessments six weeks after their procedure. This trial is important because it seeks to provide clearer guidance on which treatment might be more effective for managing this issue after an early miscarriage, ultimately helping women feel better both physically and emotionally.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Management for trophoblastic retention after early spontaneous miscarriage (\<14 weeks of amenorrhea)
• • Diagnosis of intrauterine trophoblastic retention by endovaginal pelvic ultrasound
• • Shared decision for surgical management
• • Current pregnancy desire
• Exclusion Criteria:
• • Known uterine malformation
• • Patient who has received surgical treatment for current intrauterine retention
• • Trophoblastic retention after elective termination, late miscarriage and postpartum
• • Patient with an intrauterine device (IUD)
• • Pregnancy obtained by medically assisted procreation
• • Indication for emergency surgical management for haemostatic purposes
• • Failure to obtain free, informed and written consent after a period of reflection
• • Person not affiliated or beneficiary of a national health insurance system
• • Person protected by law, under guardianship or curatorship
• • Person participating in other interventional research involving the human person