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Search / Trial NCT05794165

Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism

Launched by BRYAN COTTON · Mar 28, 2023

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Admission to trauma service
  • Polytraumatic injuries OR pelvic/long bone fracture
  • Planned admission to trauma ICU or step-down/SIMU setting (this includes STICU, SIMU/TIMU, BICU, and BIMU)
  • Informed consent obtained
  • Exclusion Criteria:
  • Prisoners (defined as those directly admitted from correctional facility)
  • Known or suspected pregnancy
  • ≥ 20% total body surface area (TBSA) burned
  • Nonsurvivable head injuries
  • Known hematologic or immunologic disorders
  • Known prehospital anticoagulant use
  • Patients initially placed on unfractionated heparin for thromboprophylaxis
  • Known allergy to Antithrombin or it's components
  • Enrollment in another interventional study unless approved by Trial Principal Investigator

About Bryan Cotton

Bryan Cotton is a distinguished clinical trial sponsor renowned for its commitment to advancing medical research and improving patient outcomes. With a strong emphasis on innovation and collaboration, the organization specializes in the development and management of clinical trials across various therapeutic areas. Bryan Cotton is dedicated to upholding the highest ethical standards and regulatory compliance, ensuring that all research is conducted with integrity and transparency. Through strategic partnerships and a focus on patient-centric approaches, the sponsor aims to accelerate the discovery of new treatments and enhance the overall quality of care in the healthcare community.

Locations

Houston, Texas, United States

Aurora, Colorado, United States

Miami, Florida, United States

Nashville, Tennessee, United States

Patients applied

0 patients applied

Trial Officials

Bryan A Cotton, MD

Principal Investigator

The University of Texas Health Science Center, Houston

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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