Establishment of a Feasibility Model for NOSE Surgery Based on Machine Learning

Launched by SIXTH AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY · Apr 3, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new way to perform surgery for patients with certain types of rectosigmoid cancers, which are cancers located in the lower part of the colon and rectum. The researchers want to see if they can use advanced computer technology, called machine learning, to help predict how well a specific surgical method called Natural Orifice Specimen Extraction Surgery (NOSES) will work. This method aims to remove tumors through natural openings in the body, which can lead to quicker recovery and less pain compared to traditional surgery.

To participate in this trial, patients should be between the ages of 65 and 74 and have been diagnosed with colorectal cancer that is not too advanced (specifically, their tumors should be at stage T3 or lower). They will also need clear imaging results, like CT or MRI scans, so the doctors can assess their condition properly. Those who have had previous treatments or have more severe cancer stages may not be eligible. If chosen to join, participants can expect thorough evaluations before and during the surgery to ensure the best possible outcome. This study is not yet recruiting participants, but it aims to help improve surgical options for patients with colorectal cancer in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients diagnosed with colorectal cancer or large adenoma who are suitable for laparoscopic colorectal surgery;
• • 2. Tumor staging ≤ T3 without invasion of surrounding organs;
• • 3. No abdominal seeding or distant organ metastasis;
• • 4. Clear and complete imaging data (CT, pelvic MRI) that can be processed by a computer;
• • 5. Feasible evaluation and determination for obtaining specimens through the rectal channel during preoperative and intraoperative assessments.
• Exclusion Criteria:
• • 1. Contraindications for laparoscopic colorectal surgery;
• • 2. Tumor staging is T4, or there are cancer nodules;
• • 3. Presence of metastasis or distant organ metastasis;
• • 4. Incomplete imaging data;
• • 5. Preoperative intestinal obstruction;
• • 6. Tumor or specimen diameter larger than the transverse diameter of the pelvic outlet;
• • 7. Previous rectal radiotherapy;
• • 8. Unsuitable evaluation and determination for obtaining specimens through the rectal channel during preoperative and intraoperative assessments.