Ketogenic Diet in Rheumatoid Arthritis (RA)

Launched by UNIVERSITY OF OKLAHOMA · Mar 23, 2023

Keywords

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Gender

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Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of RA according to the ACR/EULAR 2010 criteria for RA.
• • On stable doses of DMARDs and/ or biological agents (≥ 2 months prior to study enrollment)
• Exclusion Criteria:
• • Chronic inflammatory/ autoimmune disease other than RA (e.g. gout, inflammatory bowel disease such as Crohn's disease or ulcerative colitis, lupus, myositis, etc.)
• • Prednisone or other glucocorticoid use in the last 4 weeks (exception: intra-articular glucocorticoid injections)
• • Insulin use
• • Hospitalization in the 30 days prior to study enrollment
• • Acute or uncontrolled disease (e.g. cirrhosis, COPD, CKD)
• • Malignancy
• • Chronic infection (HIV, hep B/C, etc.)
• • Heavy drinking
• • On a ketogenic diet or exogenous ketone supplement (lses than 3 months prior to study enrollment)
• • Recent weight loss (\>5% in the last 2 months)