Single Nuclei Sequencing in Human Skeletal Muscle After Unloading
Launched by KAROLINSKA INSTITUTET · Mar 23, 2023
Trial Information
Current as of August 27, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
No description provided
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • Healthy young adult men
- Exclusion Criteria:
- • An age younger than 18 or older than 40 years
- • Contraindications to magnetic resonance imaging (MRI)
- • Contraindications to maximal intensity resistance exercise
- • Contraindications to unloading (i.e., ULLS)
- • Very high physical activity levels (determined using a standard Godin Leisure-Time Exercise Questionnaire (GLTEQ))
- • Hypertension (\>140/90 mm Hg)
- • History of malignancy
- • History of coagulation dysfunction
- • History of musculoskeletal or neurological disorders
- • History of cardiovascular disease
- • History of cerebrovascular disease
- • History of respiratory disease
- • History of gastrointestinal disease
- • History of renal disease
- • History of past or present condition requiring long-term drug prescriptions.
About Karolinska Institutet
Karolinska Institutet is a renowned medical university located in Sweden, recognized for its commitment to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the institution focuses on translating scientific discoveries into effective treatments and therapies, emphasizing patient-centered approaches. With a strong emphasis on collaboration and interdisciplinary research, Karolinska Institutet plays a pivotal role in addressing global health challenges and improving patient outcomes, leveraging its extensive network of experts and state-of-the-art facilities to drive clinical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Huddinge, Stockholm, Sweden
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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