Sonographic Parameters and Risk of Antepartum Hemorrhage in Asymptomatic Women With Placenta Previa: A Cohort Study

Launched by AIN SHAMS UNIVERSITY · Apr 5, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how certain ultrasound measurements can help predict the risk of bleeding before delivery (antepartum hemorrhage) and the need for an emergency cesarean section in women who have been diagnosed with placenta previa but have no symptoms. Placenta previa is a condition where the placenta covers the opening of the cervix, which can lead to complications during pregnancy. The researchers will look at factors like the length of the cervix and how thick the placenta is to see if these measurements can indicate potential risks.

To participate in this study, women need to be between 28 and 37 weeks pregnant and diagnosed with placenta previa, meaning the placenta is directly over the cervix. However, those with multiple pregnancies, a history of bleeding during the current pregnancy, or certain other health issues won’t be eligible. Participants will have regular ultrasounds to measure the specified parameters, and the study aims to improve understanding of how to manage pregnancies with placenta previa more effectively. If you or someone you know fits the criteria and is interested, this could be an important opportunity to contribute to better care for future patients.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Asymptomatic women diagnosed with placenta previa according to RCOG (GTG No. 27a, 2018): placenta lies directly over the internal os for pregnancies more than 16 weeks' gestation on transabdominal or transvaginal scanning.
• • Gestational age between 28 till 37 weeks' gestation (as delivery should be considered between 36 and 37 weeks of gestation for women presenting with uncomplicated placenta previa)
• Exclusion Criteria:
• • Multiple pregnancies.
• • Threatened preterm labor or preterm rupture of membranes.
• • History of bleeding in the current pregnancy.
• • Polyhydraminos (AFI \> 25 cm).
• • History of cervical surgery (cone biopsy).
• • Presence of cervical cerclage.
• • Maternal use of vaginla progesterone.
• • History of maternal disease (hypertensive, DM, Cardiac).
• • Fetal malformation or growth restriction