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Search / Trial NCT05802940

Low Dose Aspirin Alerts in High-Risk Pregnancies

Launched by GEISINGER CLINIC · Apr 6, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how an electronic tool, called a best practice alert, can help healthcare providers recommend low-dose aspirin to pregnant women who are at high risk of developing a condition called preeclampsia. Preeclampsia can lead to serious complications for both the mother and baby, and taking low-dose aspirin may help reduce this risk. The researchers believe that by using this electronic tool, more healthcare providers will suggest low-dose aspirin to their patients than they currently do.

To participate in this study, women need to be receiving prenatal care at Geisinger and have their first prenatal visit before they are 28 weeks pregnant. They must also be identified as high risk for preeclampsia based on specific guidelines, meaning they have at least one risk factor for the condition. Unfortunately, women who are not pregnant, have not had an early prenatal visit, or have certain medical reasons that prevent them from taking aspirin will not be eligible. Participants can expect to help improve care for future patients while potentially receiving personalized recommendations about low-dose aspirin during their pregnancy.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Receiving prenatal care within Geisinger
  • Initial prenatal visit prior to 28 weeks gestation
  • Determined to be high risk for preeclampsia based on the modified United States Preventive Services Task Force and American College of Obstetrics and Gynecology criteria (at least 1 high risk factor)
  • Exclusion Criteria:
  • Not pregnant
  • No prenatal visit prior to 28 weeks gestation
  • Maternal-Fetal Medicine only visits
  • Not meeting the modified USPSTF high-risk criteria
  • Contraindication to aspirin, including allergy

About Geisinger Clinic

Geisinger Clinic is a leading healthcare organization based in Pennsylvania, recognized for its commitment to innovative patient care and research. As a clinical trial sponsor, Geisinger Clinic integrates cutting-edge medical research with a focus on improving health outcomes through evidence-based practices. The organization leverages its extensive electronic health record system and diverse patient population to facilitate comprehensive clinical studies that advance medical knowledge and enhance therapeutic options. With a strong emphasis on collaboration and community engagement, Geisinger Clinic aims to translate research findings into practical solutions that benefit patients and the healthcare system as a whole.

Locations

Danville, Pennsylvania, United States

Patients applied

0 patients applied

Trial Officials

A. Dhanya Mackeen, MD, MPH

Principal Investigator

Geisinger Clinic

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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