Phenotypic Characteristics of Superlean Individuals Including Gut Microbiome

Launched by SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY ,CHINESE ACADEMY OF SCIENCES · Mar 27, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a specific group of very thin individuals, known as "superlean" individuals, who have a body mass index (BMI) of less than 18.5. The researchers want to learn more about what makes these people different from those with a normal BMI (between 21.5 and 25). They will look at various factors such as body composition, eating habits, hormone levels, genetics, and the bacteria that live in the gut. The goal is to gain a better understanding of why some people are superlean and how their health is affected.

To participate in the study, you need to be between 25 and 40 years old and fall into one of two groups: either superlean or in the normal BMI range. However, certain health conditions will exclude you from participation, such as metabolic diseases, eating disorders, or being treated for weight loss. If you join the study, you can expect to provide information about your eating habits and undergo tests to evaluate your body composition and gut health. This research could help improve our understanding of body weight and health behaviors in individuals.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Control group (21.5≤ BMI\<25), Superlean group (BMI≤18.5)
• • Age between 25-40 years old
• Exclusion Criteria:
• • Having metabolic diseases or eating disorders
• • Recent weight loss due to various disease causes
• • Being treated for weight loss
• • Having an infectious disease
• • Pregnant and lactating women
• • People with blood sickness, pathological hypo- or hypertension
• • People suffering from claustrophobia
• • No metal implants in the body
• • Use of antibiotics, probiotics, oral laxatives, etc. within 8 weeks