Traditional Dietary Advice Versus Low FODMAP Diet in Postprandial Functional Dyspepsia

Launched by SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST · Mar 30, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring two different dietary approaches to help people with a condition called postprandial functional dyspepsia (PDS), which causes discomfort after eating. The trial will compare traditional dietary advice, which suggests eating small meals and avoiding certain foods, to a low FODMAP diet that restricts specific types of carbohydrates found in many common foods. Researchers want to see which diet helps relieve symptoms better over a six-week period.

To participate, you need to be between 18 and 75 years old, have been diagnosed with PDS, and have had a normal upper GI endoscopy in the last three years. You also need to be able to read and understand English and have online access. During the trial, participants will complete questionnaires to track their symptoms and how they feel overall. It's important to note that people with certain health conditions, those who have had major surgeries, or are currently on specific medications may not be eligible for this study. If you think this study might be relevant for you or someone you know, it could be a good opportunity to explore dietary strategies for managing PDS.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Fulfil Rome IV symptoms criteria for postprandial functional dyspepsia
• • Normal upper gastrointestinal endoscopy within last 3years
• • Online access
• • English literate
• Exclusion Criteria:
• • Organic gastrointestinal diseases (e.g. inflammatory bowel disease, GI cancer, coeliac disease)
• • Major abdominal surgery (except laparoscopy, appendectomy, cholecystectomy)
• • Documented H.pylori in the last 3 months
• • History of eating disorders
• • Body mass index \<20
• • Current dietary interventions
• • Current use of opioids or anti-inflammatory drugs
• • Severe systemic disease (e.g. cardiac, renal, respiratory) necessitating frequent medical consultations)
• • Pregnant
• • Diabetes mellitus
• • Scleroderma
• • Memory impairment