Exploring the Difference Between Gastric Cardia Cancer and Non-cardia Gastric Cancer Based on Multiomics

Launched by QILU HOSPITAL OF SHANDONG UNIVERSITY · Apr 2, 2023

Keywords

ClinConnect Summary

This clinical trial is studying two types of stomach cancer: gastric cardia cancer, which occurs at the top part of the stomach near the esophagus, and non-cardia gastric cancer, which occurs in other parts of the stomach. Researchers want to find out how these two types differ by looking at various biological samples, like saliva and blood, from people with gastric cancer. By analyzing these samples, they hope to identify unique characteristics that could help with early detection of gastric cancer.

To participate in this study, individuals must be between 18 and 75 years old and have had a confirmed diagnosis of gastric cancer through an endoscopic examination. However, people who have had recent stomach surgery, certain medical treatments, or other digestive diseases that could affect the results won't be eligible. This trial is currently not recruiting participants, but it aims to gather important information that could lead to better screening and treatment options for gastric cancer in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Study population signing informed consent form
• • Age: 18-75 years old
• • The study population must underwent endoscopic examination and was confirmed by pathological diagnosis as gastric cancer: including high-level intraepithelial neoplasia, early gastric cancer, and advanced gastric cancer.
• Exclusion Criteria:
• • Those who have undergone gastrointestinal surgery within the past 1 year; Patients who have undergone neoadjuvant chemotherapy and have developed tumors in the residual stomach after previous partial gastrectomy.
• • Those who have used proton pump inhibitors, antibiotics, probiotics, and prebiotics daily within the past month, and those who have recently received hormone therapy.
• • People with infectious diseases and other digestive system diseases that interfere with the experimental results, such as inflammatory bowel disease, irritable bowel syndrome, etc.