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Search / Trial NCT05814250

Ultrasonography in Children With First Febrile Urinary Tract Infection

Launched by IRCCS BURLO GAROFOLO · Apr 13, 2023

Trial Information

Current as of August 25, 2025

Recruiting

Keywords

Urinary Tract Infection Kidney Ultrasound Congenital Anomalies Of The Kidney And Urinary Tract

ClinConnect Summary

This clinical trial is studying the use of kidney ultrasounds (KUS) in young children who have their first urinary tract infection (UTI) with a fever. The goal is to find out if the presence of certain germs and the frequency of UTIs can help predict whether a KUS will show any problems. Typically, doctors recommend a KUS for all children after their first febrile UTI to check for any underlying kidney issues, but there's ongoing debate about whether this is necessary for everyone.

To be eligible for this study, children must be between 2 months and 3 years old and have had their first UTI. However, those with previous UTIs, those on preventive antibiotics, or those with known kidney problems are not included. Participants will undergo a KUS to see if any kidney problems can be identified based on their symptoms and the germs causing their infection. This research could help determine better ways to evaluate children with UTIs and potentially reduce unnecessary tests.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • - Patient with first episode of fUTI that subsequently do KUS.
  • Exclusion Criteria:
  • patients with previous episodes of UTIs
  • patients on antibiotic prophylaxis
  • previous finding of malformative uropathies or cystic disease
  • prenatal diagnosis of CAKUT with the following parameters: Presence of oligohydramnios, alterations in renal number, location and echo structure, bladder alteration, dilations of the renal pelvis and ureters

About Irccs Burlo Garofolo

IRCCS Burlo Garofolo is a prestigious research institute located in Trieste, Italy, dedicated to advancing pediatric healthcare through innovative clinical research. As a recognized IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), it focuses on a wide range of pediatric diseases, emphasizing the integration of clinical care and scientific research to improve patient outcomes. The institute collaborates with various national and international partners, fostering an environment of rigorous scientific inquiry and excellence in medical practice. Its commitment to ethical standards and patient safety ensures that all clinical trials conducted under its auspices contribute meaningful advancements in pediatric medicine.

Locations

Trieste, , Italy

Firenze, , Italy

Milano, , Italy

Patients applied

0 patients applied

Trial Officials

Marco Pennesi, MD

Study Director

IRCCS materno infantile Burlo Garofolo

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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