E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness

Launched by NYU LANGONE HEALTH · Apr 4, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how e-cigarettes can help people with serious mental illnesses who smoke regular cigarettes reduce their smoking. The study will involve participants who currently smoke at least five cigarettes a day and are diagnosed with conditions like schizophrenia or bipolar disorder. These participants will receive support through counseling and text messages to help them, and they will be randomly divided into two groups. One group will use e-cigarettes, while the other will use nicotine replacement therapies, like patches or lozenges, to see which method is more effective in helping them cut back on smoking.

To be eligible for the trial, participants should be at least 21 years old, own or have access to a mobile phone, and be willing to provide contact information for follow-up. They shouldn't be pregnant, have recently used other tobacco products, or be actively trying to quit smoking. Overall, participants can expect to receive guidance and support as they try to reduce their cigarette smoking, while also contributing to valuable research that may help others in similar situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Currently smokes 5 or more CPD
• • Willingness and ability to provide informed consent
• • Age of at least 21 years
• • Has SMI diagnosis (such as Schizophrenia, Schizoaffective disorders, Bipolar disorder, Depressive disorders, Trauma and stressor related disorders etc.) as determined using the MINI tool
• • Interested in reducing CC smoking but not necessarily trying to quit
• • Own a mobile phone or have regular access to a mobile phone
• • Able to provide an additional contact to improve follow-up rates
• Exclusion Criteria:
• • Is pregnant or breastfeeding
• • Used tobacco other than CC in the past 2 weeks (e.g., EC, cigarillo)
• • Currently engaged in an attempt to quit CC
• • Change in dose of their psychotropic medication(s) in the last 30 days
• • Meeting DSM-V criteria for current alcohol or substance use disorder except for nicotine use disorder and active mild alcohol or substance use disorders.
• • Past month suicidal ideation/suicide attempt and/or psychiatric hospitalization in the last 30 days