MS-DETECT: Early Detection of Multiple Sclerosis Progression With MSCopilot® Detect

Launched by AD SCIENTIAM · Apr 3, 2023

Keywords

ClinConnect Summary

The MS-DETECT trial is studying a smartphone app called MSCopilot® Detect, which is designed to help patients with Multiple Sclerosis (MS) monitor their symptoms from home. The main goal of the study is to improve how doctors can track the progression of MS, whether it's due to relapses (sudden worsening of symptoms) or gradual changes over time. Researchers also want to make sure the app is safe and easy to use, and they aim to see if it can detect changes in a patient's condition early on.

To participate in the study, you need to be an adult aged 30 to 65 with a specific type of MS and certain levels of disability that have been stable for the last three months. You'll need to have a smartphone that meets certain requirements and be comfortable using it. If you join, you'll participate in a few visits over two years, where you'll fill out questionnaires about your symptoms and quality of life, and complete digital tests to help track your condition. The study is currently recruiting participants in several countries, including the United States, Canada, and various European nations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients living with RRMS or SPMS, aged 30 to 65
• • EDSS score between 2.5 to 6.5 points
• • With a disease duration \> 5 years
• • Clinically stable during the last 3 months before inclusion (no relapses, no disability progression)
• • No change in the DMT\* during the last 3 months before inclusion
• • Receiving optimal symptomatic treatments at baseline (clinician's judgment)
• • Owns a personal smartphone which mobile operating system is above 14 for IOS (iPhone) and 8 for Android included with a good internet connexion
• • Able to use a smartphone
• • Able to read language in wich the mobile application is available and able to understand pictograms.
• • Applicable to patients enrolled in France only: affiliated to a social security system.
• Exclusion Criteria:
• • Medically unstable conditions that may hinder patient's ability to comply with the study procedures
• • Inability to use a smartphone or MSCopilot® Detect application
• • Patient with corrected visual acuity less than 4/10 (Monoyer) or 20/50 (Snellen at 20 feet) or +0,4 (LogMAR)
• • Pregnancy and nursing women
• • Persons under guardianship or curatorship
• • Current drugs or/and alcohol abuse that could influence performance on the tests (clinician's judgment)
• • Patients have participated in another clinical study within the previous 30 days of screening or are currently participating in another study that, in the opinion of the Investigator, might interfere with the patient's full participation in the study or confound the assessment of the patient or outcome of the study.