Point-of-care Low-field MRI in Acute Stroke

Launched by UNIVERSITY OF L'AQUILA · Apr 3, 2023

Keywords

ClinConnect Summary

This clinical trial, titled "Point-of-care Low-field MRI in Acute Stroke," is looking to evaluate how effective a type of MRI scanner, called low-field MRI, is for quickly diagnosing strokes in patients who arrive at the emergency department. The study will involve patients suspected of having a stroke, and it will take place in three hospitals in Italy. Researchers will compare the results of low-field MRI with traditional imaging methods to determine the best treatment options for patients. Additionally, they plan to use the data collected to develop artificial intelligence tools that can help interpret MRI images more accurately.

To be eligible for the trial, patients must have symptoms that suggest a stroke and should have experienced these symptoms within the last 24 hours. They will need to provide informed consent, which means they understand the study and agree to participate. However, individuals who have conditions that prevent them from safely undergoing an MRI or who cannot give consent will not be included. Participants can expect to undergo imaging tests and receive care based on the results, contributing valuable information to improve stroke diagnosis and treatment in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. symptoms suggestive of acute stroke (acute onset of a focal neurological deficit which can be referred to the involvement of a specific CNS region);
• • 2. stroke onset \<24 h since when the patient was last known healthy;
• • 3. written informed consent provided by the patient himself or by proxy (for unconscious patients, cognitively impaired or aphasic).
• Exclusion Criteria:
• • 1. symptoms not indicative of acute stroke (e.g. syncope, tonic or clonic activity, dizziness or wooziness alone, confusion and amnesia alone, subacute or chronic development of a focal neurological deficit);
• • 2. inability to undergo LF-MRI due to critically impaired vital functions (e.g. hemodynamically unstable patients, need of immediate life-saving maneuvers);
• • 3. implanted ferromagnetic devices potentially interfering with LF-MRI (e.g. cochlear implants);
• • 4. impossibility to achieve written informed consent.