Efficacy of Local Infiltration of Tranexamic Acid and Lidocaine in Tonsillar Bed on Postoperative Bleeding and Pain During Tonsillectomy Surgery: Prospective, Randomized, Control Study
Launched by MOHAMED · Apr 5, 2023
Trial Information
Current as of August 02, 2025
Completed
Keywords
ClinConnect Summary
The control of postoperative pain in children after tonsillectomy is a crucial issue. After a tonsillectomy, it is crucial to receive enough postoperative analgesia since discomfort limits swallowing, increases the risk of dehydration, infection, and subsequent bleeding, and can impede a quick recovery and painless convalescence. Immediately following surgery and during the first 24th hours, this pain is at its most intense (1).
The main reason for reoperation and mortality in children who have had tonsillectomy is post-tonsillectomy hemorrhage (PTH). These two categories of PTH as primary...
Gender
ALL
Eligibility criteria
- • Inclusion criteria
- • 1. Male or female child between 4 and 12 years old
- • 2. ASA one and two, planned for an elective tonsillectomy
- • 3. Patients having 4 or more episodes of tonsillitis in the last year, 5 or more episodes in the previous two years, or 7 episodes in the previous three years.
- • Exclusion criteria
- • 1-Children with diabetes mellitus, problems of the heart, kidneys, or liver 4-Obstructive sleep apnea syndrome 5-blood disorders, or a propensity to hemorrhage 6-patients suspected of an allergy to the drug being administered, and those undergoing concurrent surgery such as an adenoidectomy or tongue tie.
About Mohamed
Mohamed is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes through innovative therapeutic solutions. With a focus on rigorous scientific methodologies and ethical standards, Mohamed collaborates with leading researchers and institutions to conduct high-quality clinical studies across various therapeutic areas. The organization prioritizes patient safety and data integrity, ensuring that each trial contributes valuable insights to the medical community. Through its strategic partnerships and commitment to excellence, Mohamed aims to accelerate the development of groundbreaking treatments that address unmet medical needs.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Trial Officials
abdalla mohamed abdalla, MD
Principal Investigator
AZHAR
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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