The Prevalence, Risk Factors and Optimal Biopsy Protocol of BE

Launched by E-DA HOSPITAL · Apr 14, 2023

Keywords

ClinConnect Summary

This clinical trial is studying Barrett's Esophagus (BE), a condition where the lining of the esophagus changes, which can lead to more serious health issues. The researchers want to find out the best way to take biopsies, which are small samples of tissue, to see if there are any harmful changes called dysplasia or the presence of goblet cells. They are particularly focused on understanding how many biopsies are needed and how effective they are in detecting these changes, especially in Asia.

To participate in this study, you need to be an adult with a specific type of esophagus lining called a columnar-lined esophagus. However, you cannot join if you have had certain previous treatments for Barrett's Esophagus, any history of cancer in the upper digestive tract, or if you have certain medical conditions that could complicate the procedure. If you decide to participate, you can expect to undergo biopsies as part of the evaluation process, which will help improve the understanding and management of Barrett's Esophagus for future patients. The study is currently recruiting participants of all genders, and it aims to gather important information that could lead to better care for those with this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults with columnar-lined esophagus
• Exclusion Criteria:
• • A prior history of endoscopic treatment for Barrett's Esophagus
• • A prior history of upper gastrointestinal malignancy
• • A prior history of total or subtotal gastrectomy
• • Esophageal varices noted during the procedure
• • Uncontrolled coagulopathy
• • Taking antiplatelet drug or anticoagulant